A multi-ingredient Japanese beauty drink bringing together a PUA exosome-containing extract, food-derived nucleotides, fermented collagen, fermented placenta concentrate and selected beauty nutrients.
12bottles30 mLeachMade in Japan
美しさを、細胞コミュニケーションの発想から
Why it was created
Beauty is not only what appears at the surface.
Skin appearance reflects a network of structural, barrier and nutritional processes working together. EXOSOME MATRIX DRINK was conceived in Japan as a concentrated daily ritual for that wider biological picture—not as another single-ingredient collagen drink.
Its architecture brings together a signature PUA exosome-containing extract, food-derived nucleotides, fermented collagen peptides, fermented and aged placenta concentrate, rice ceramides and selected beauty nutrients. Each layer has a distinct role; together they form a considered matrix designed for premium beauty and longevity portfolios.
A considered Japanese multi-ingredient approach
Cell biology · extracellular vesicles
Small carriers. Complex conversations.
A closer look at how cells release membrane-bound vesicles and how their molecular cargo can participate in communication between cells.
A source cell releases extracellular vesicles enclosed by a lipid membrane.
General vesicle biology. Delivery to tissues and effects after consuming this drink are not established by this illustration.
Formula architecture
Signals, structural nutrients and a considered beauty matrix.
01Signal platformThe PUA exosome-containing extract anchors the concept of extracellular communication—the biological language that inspired the formula.02Structural beautyRice ceramides, fermented collagen peptides and hyaluronic acid support the formula’s structure-and-hydration design.03Nucleotide matrixSalmon-milt-derived DNA-Na and yeast-derived RNA bring a complementary food-derived nucleotide layer.04Japanese bioactive complexFermented horse placenta extract, RG92 green algae, royal jelly, CoQ10 and B vitamins complete the architecture.
Inside the formula
Every ingredient has a defined role.
Quantities shown are based on the current 30 mL bottle label and product dossier supplied by Yotsuba Japan. Market labels may differ.
Select an ingredient to explore its source or food comparison +
DNA-Na · Inside the raw material
≈ 215mg
DNA-Na within the declared ingredient
86% DNA-Na
Ingredient amount
250 mg
Selected constituent
215 mg
Raw-material calculation & source+
Food-derived nucleotide source containing DNA-Na 86%. 250 mg describes the prepared ingredient. The separate DNA-Na quantity is approximately 215 mg on the declared composition basis. A selected constituent and the whole source material describe different compositional levels.
This compares selected constituent content, not complete nutrition, digestion, absorption or health effects. Composition varies with source and processing. Images are illustrative, not measured portions or eating recommendations. This is a declaration-based constituent calculation, not an extraction yield, whole-food equivalent or independent finished-product assay.
Food quantities compare selected constituent content only. Form comparisons explain the relationship between a familiar source and a prepared ingredient; they do not imply a portion or extraction ratio. Foods and supplements differ in nutrition, absorption and health effects. Images are illustrative, not measured portions or eating recommendations.
Salmon Milt Extract: ingredient perspective open
One formula · several complementary layers
Precision in every layer of the matrix.
The formula is deliberate: several complementary ingredient systems brought together in a precise liquid composition. Its value is not one fashionable ingredient in isolation, but the logic of the complete matrix.
Individual 30 mL bottle12-bottle presentationConcentrated liquid ritual
Ingredient evidence library
Built for a more informed conversation.
Important distinctionThese publications examine individual ingredients or related ingredient preparations. They are not clinical trials of EXOSOME MATRIX DRINK and do not prove that the finished product produces the same outcomes.
Equine placental extractHuman RCT
Facial skin quality in healthy adult women
A randomised, double-blind, placebo-controlled study in 29 women evaluated 220 mg/day for four weeks. The between-group pattern for cheek melanin index differed, while hydration and TEWL did not show a significant between-group difference.
Collagen peptidesHuman clinical study
Skin hydration and barrier-related measures
Oral collagen-peptide intake was associated with increased stratum-corneum and epidermal water content and reduced transepidermal water loss. Ingredient type and dose should be compared with the finished formula before extrapolation.
Rice ceramidesHuman prospective study
Skin barrier function and hydration
A prospective study assessed oral rice-derived ceramides in relation to skin-barrier measures. The design was open-label, so it provides supportive—not confirmatory—clinical evidence.
Food-derived DNA-NaPreclinical
Stress-related inflammatory signalling
A mouse study found changes in stress-related and hippocampal inflammatory markers with salmon-milt-derived DNA-Na. This is mechanistic animal evidence and cannot establish a human clinical benefit.
Professional product data
Complete details, clearly organised.
The quantitative active formula is presented above. Here, professionals can review the complete ingredient declaration, allergens, format, nutrition information, directions and handling information.
Allergen information: Contains salmon, fish gelatin and peach. Royal jelly may cause an allergic reaction in sensitive individuals. The approved market-specific label remains authoritative.
Format & serving02
Product category Beverage with 20% mixed fruit juicePackage 360 mL totalPresentation 12 bottles × 30 mLServing unit 1 bottleSuggested use 1 bottle every 1–2 daysServing note Best enjoyed chilled
Nutrition per 30 mL bottle03
Energy 14.5 kcalProtein 0.7 gFat 0 gCarbohydrate 7.9 gSalt equivalent 0.218 gNiacin 250 μgCalcium pantothenate 219 μgVitamin B6 181 μgVitamin B2 125 μgFolic acid 100 μgBasis Per 30 mL bottle
Use, storage & precautions04
Store away from high temperature and direct sunlight, in a cool place. Drink immediately after opening. If ingredients float or settle, this does not indicate a quality problem. People with food allergies should review the full ingredient declaration, and anyone for whom the product does not suit their constitution should stop use. Be careful not to injure yourself on the edge of the cap. This is a food supplement, not a medicine; a balanced diet remains the foundation of health.
日本MADE IN JAPAN
Japanese quality & provenance
Designed as a flagship, documented as a professional product.
Developed and manufactured in Japan with a dossier-led approach for international professional review. Manufacturing, specification and market documentation are provided through Yotsuba Japan’s official partner network, subject to destination-market requirements.
Frequently asked
Clear answers, without overclaiming.
01What makes this different from a conventional collagen drink?+
EXOSOME MATRIX DRINK is not built around collagen alone. It combines a signature exosome-powder platform with food-derived nucleotides, fermented collagen peptides, rice ceramides and complementary beauty nutrients in one considered matrix.
02Who is the formula designed for?+
It was developed for premium beauty, healthy-ageing and professional wellness portfolios. Individual suitability should always be assessed against the destination-market label and, where appropriate, by a qualified professional.
03How should it be taken?+
The current label suggests one 30 mL bottle every one to two days, best enjoyed chilled. Follow the approved market-specific label for the destination market.
04Are the cited studies trials of this finished drink?+
No. The evidence library relates to individual ingredients or comparable ingredient preparations. It is included to explain the scientific rationale—not to claim that the finished product reproduces every published outcome.
05Where is it made?+
The formula is developed and manufactured in Japan. Product documentation for professional review is available from Yotsuba Japan and its official partners.
Food supplement · Not a medicine
Product information is educational and intended for professional portfolio review. It is not medical advice and is not intended to diagnose, treat, cure or prevent disease. Suitability, permitted claims and labelling must be assessed for each destination market.
EXOSOME MATRIX DRINK
A Japanese beauty ritual, engineered beyond the ordinary.
Detailed product documentation is available to verified clinics, professionals and authorised partners, subject to individual review.Available exclusively through authorised Yotsuba Japan partners.
