Yotsuba Japan
← All products

Women’s Daily Balance · 30-day system

HORMONE
BALANCESOY ISOFLAVONES AGLYCONE

A Japanese women’s wellness formula combining 30 mg of soy isoflavones in aglycone form with wild yam, pomegranate, a lactobionic-acid fermented ingredient, seaweed calcium and vitamin D.

180tablets6per dayMade in Japan
Her Harmony Soy Isoflavones Aglycone box and bottle by Yotsuba Japan

Why it was created

A thoughtful daily ritual
for changing life stages.

The formula is centred on soy isoflavones in the aglycone form, quantified at 30 mg per six-tablet daily serving.

Five complementary botanical, fermented and mineral ingredients create a broader women-focused nutrition concept for peri- and post-menopausal portfolios.

Soy aglycone · botanical layer · calcium & vitamin D
Hormone Balance bottle and tablets arranged in a clean pearl-white flatlay

Biochemistry · receptor context

A plant-derived structure.
A context-dependent signal.

Explore why molecular structure matters when isoflavones are discussed in relation to estrogen receptors.

Explore ingredient evidence
YOTSUBA JAPAN FORMULA STUDY
Aglycones are isoflavone forms without the attached sugar group of their glycosides. Isoflavones can interact with estrogen receptors; interaction varies by compound and receptor subtype. Receptor subtype, tissue, dose and individual biology all influence the response. General biological context, not a clinical result for this supplement. Simplified and not to scale.ER
01/ 03

Aglycone form

Aglycones are isoflavone forms without the attached sugar group of their glycosides.

General biological context, not a clinical result for this supplement. Simplified and not to scale.

Formula architecture

One aglycone core.
Five complementary layers.

01
Soybeans and soybean leaves representing the source of soy isoflavones
Soy isoflavones aglycone30 mg of soy isoflavones already presented in the free aglycone form.
02
Wild yam roots and leaves representing the botanical extract
Wild yam extractA botanical extract included in the women-focused daily formula.
03
Pearlescent molecular-form illustration representing the lactobionic-acid fermented ingredient
Lactobionic layerA lactose-fermented ingredient containing lactobionic acid.
04
Pomegranate fruit and seeds representing the fruit extract
Pomegranate extractPomegranate fruit extract adds a complementary botanical dimension.
05
Pearlescent mineral composition representing the marine-derived calcium ingredient
Seaweed calciumA marine-derived calcium ingredient paired with vitamin D.
06
Golden and pearlescent micronutrient illustration representing vitamin D
Vitamin DIncluded as part of the formula’s mineral-nutrition layer.
Hormone Balance bottle held among spring cherry blossoms in Japan

The women’s daily ritual

Quiet consistency,
six tablets a day.

A measured 30-day presentation turns a layered formulation into a simple daily routine. The editorial cherry-blossom setting reflects Japanese provenance without changing the product’s authentic packaging.

Six tablets dailySix formula componentsThirty-day presentation

Ingredient evidence library

Evidence, with the
right boundaries.

Important distinctionThe references below concern individual nutrients, isoflavone formats or supplemental isoflavones. They are not clinical trials of the complete Yotsuba Japan HORMONE BALANCE formula.
Soy isoflavone aglyconesIn-vitro receptor study

Receptor interaction depends on molecular form

Human estrogen-receptor binding assays found that soy isoflavone aglycones can interact differently with ERα and ERβ. This mechanistic evidence does not predict an individual response or show that the finished formula normalises hormone levels.

Isoflavone formHuman pharmacokinetic study

Aglycone and glycoside formats

A human study compared soy isoflavone aglycones with glucosides and reported differences in absorption timing and exposure. The tested preparations and doses differ from this complete Yotsuba Japan formula.

Soy isoflavonesEFSA risk assessment

Peri- and post-menopausal use

EFSA reviewed supplemental isoflavone safety for peri- and post-menopausal women. This is a risk assessment, not proof that the finished product treats menopausal symptoms.

Calcium + vitamin DNIH nutrient reference

A complementary nutrient pairing

NIH explains that calcium is a structural component of bones and teeth and that vitamin D is required for active intestinal calcium absorption. The product label does not state an elemental calcium amount.

Professional product data

Complete details,
clearly organised.

Professionals can review the complete Japanese ingredient declaration, allergens, format, nutrition, directions and handling information below.
Complete ingredients & allergens01

Current Japanese composition: Seaweed calcium (manufactured in the United Kingdom), wild yam extract, lactose-fermented product containing lactobionic acid, pomegranate fruit extract powder, maltitol, soy isoflavone extract containing aglycones, crystalline cellulose, silicon dioxide, calcium stearate and vitamin D.

Allergen information: Contains milk and soybean. The approved destination-market label remains authoritative.

Format & daily serving02
Format 180 tabletsDaily serving 6 tabletsSupply 30 daysNet content 63.0 gTablet weight 350 mgDaily serving weight 2.1 g
Nutrition per daily serving03
Energy 6.13 kcalProtein 0.01 gFat 0.07 gCarbohydrate 1.37 gSalt equivalent 0.008 gSoy isoflavones aglycone 30 mg

Values are stated on the current Japanese package per six-tablet daily serving (2.1 g). No individual quantities are declared for the other ingredients.

Use, storage & precautions04

Take six tablets daily with water or warm water. Store away from high temperature, humidity and direct sunlight. If the product does not agree with your constitution, reduce the amount or discontinue use. People taking medicines or receiving medical care should consult a physician before use. Consume promptly after opening. Natural variations in colour may occur without affecting quality. This is a health food product, not a medicine.

日本GMP
PRODUCTION

Japanese quality & provenance

Developed as a complete
30-day women’s system.

The 180-tablet presentation is produced in Japan under the GMP manufacturing standards declared on the current product packaging.

Frequently asked

Clear answers,
without overclaiming.

01What is “aglycone”?+

In soy, isoflavones can occur attached to a sugar group as glycosides. Aglycone describes the corresponding sugar-free molecular form. The animation on this page is conceptual and is not a simulation of absorption.

02What is the daily serving?+

The current Japanese directions indicate six tablets per day with water or warm water. Follow the approved destination-market label.

03What amount is declared on the Japanese package?+

The current Japanese package declares 30 mg of soy isoflavones aglycone per daily serving of six tablets. It does not state individual quantities for the other ingredients.

04What allergens are declared?+

The current Japanese ingredient declaration identifies milk and soybean. The approved market-specific label remains authoritative.

05Who should seek professional advice?+

Anyone who is pregnant or breastfeeding, receives medical care, takes medication, or has a hormone-sensitive medical history should consult an appropriate healthcare professional before use.

Food supplement · Not a medicine

Product information is educational and intended for professional portfolio review. It is not medical advice and is not intended to diagnose, treat, cure or prevent disease. Suitability, permitted claims and labelling must be assessed for each destination market.

HORMONE BALANCE · Women’s Daily Balance

A precise aglycone core,
shaped into a daily ritual.

Detailed product documentation is available to verified clinics, professionals and authorised partners, subject to individual review.Available exclusively through authorised Yotsuba Japan partners.

Restricted professional access

Request professional
product information.

Detailed product documentation is released only after review by Yotsuba Japan or an authorised partner.
01 Contact details
02 Professional profile
03 Request details